Staurosporine derivatives substituted at methylamino nitrogen

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540545, A61K 3155, C07D49822

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active

050933302

ABSTRACT:
N-substituted derivatives of staurosporine of the general formula

REFERENCES:
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Tamaoki et al., Biochem. Biophys. Res. Comm., vol. 135, pp. 397-402 (1986).
Takahashi et al, J. Antibiotics, vol. 40, No. 12, pp. 1782-1784 (1987).
PCT 89/07105 Abstract.
Weinreb, Heterocycles, vol. 21, pp. 309-324 (1984).
Furusaki, J. Chem. Soc. Chem. Commun., vol. 18, 800-1 (1978).
Furusaki, Bull. Chem. Soc. Jpn., vol. 55, pp. 3681-3685 (1982).

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