Preparation of quetiapine

Details Preparation of quetiapine Preparation of quetiapine

2011-01-04

2011-01-04

Coleman, Brenda L (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

active

07863441

ABSTRACT:
The present invention discloses a process for the preparation of quetiapine, which comprises the ring closure of a compound of the formula shown below, as well as novel intermediates in the process.

REFERENCES:
patent: 3539573 (1970-11-01), Schmutz et al.
patent: 2007/0111986 (2007-05-01), Hilden et al.
patent: WO-01/55125 (2001-08-01), None
patent: WO-02/083624 (2002-10-01), None
Database Beilstein Crossfire Beilstein Institut Zur Foerderung Der Wissenschaften, Frankfurt, Main, DE; Citation No. 5562436 1988, XP002316545.
Warawa E J et al., Journal of Medicinal Chemistry, American Chemical Society. Washington, US, vol. 44, Feb. 1, 2001, pp. 372-389, XP002213291, ISSN: 0022-2623.

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