Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2011-07-19
2011-07-19
Gussow, Anne M. (Department: 1643)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C424S130100, C424S134100, C424S178100, C424S183100, C530S391100, C530S391300, C530S391700
Reexamination Certificate
active
07982012
ABSTRACT:
The present invention provides novel anti-cytomegalovirus antibodies and related compositions and methods. These antibodies may be used in the diagnosis, prevention, and treatment of cytomegalovirus infection.
REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 3896111 (1975-07-01), Kupchan et al.
patent: 4137230 (1979-01-01), Hashimoto et al.
patent: 4151042 (1979-04-01), Higashide et al.
patent: 4248870 (1981-02-01), Miyashita et al.
patent: 4256746 (1981-03-01), Miyashita et al.
patent: 4260608 (1981-04-01), Miyashita et al.
patent: 4265814 (1981-05-01), Hashimoto et al.
patent: 4294757 (1981-10-01), Asai
patent: 4307016 (1981-12-01), Asai et al.
patent: 4308268 (1981-12-01), Miyashita et al.
patent: 4308269 (1981-12-01), Miyashita et al.
patent: 4309428 (1982-01-01), Miyashita et al.
patent: 4313946 (1982-02-01), Powell et al.
patent: 4315929 (1982-02-01), Freedman et al.
patent: 4317821 (1982-03-01), Miyashita et al.
patent: 4322348 (1982-03-01), Asai et al.
patent: 4331598 (1982-05-01), Hasegawa et al.
patent: 4361650 (1982-11-01), Asai et al.
patent: 4362663 (1982-12-01), Kida et al.
patent: 4364866 (1982-12-01), Asai et al.
patent: 4371533 (1983-02-01), Akimoto et al.
patent: 4424219 (1984-01-01), Hashimoto et al.
patent: 4450254 (1984-05-01), Isley et al.
patent: 4485045 (1984-11-01), Regen
patent: 4544545 (1985-10-01), Ryan et al.
patent: 4554101 (1985-11-01), Hopp
patent: 4676980 (1987-06-01), Segal et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4975278 (1990-12-01), Senter et al.
patent: 5013556 (1991-05-01), Woodle et al.
patent: 5053394 (1991-10-01), Ellestad et al.
patent: 5208020 (1993-05-01), Chari et al.
patent: 5229275 (1993-07-01), Goroff
patent: 5416064 (1995-05-01), Chari et al.
patent: 5500362 (1996-03-01), Robinson et al.
patent: 5545806 (1996-08-01), Lonberg et al.
patent: 5545807 (1996-08-01), Surani et al.
patent: 5567610 (1996-10-01), Borrebaeck et al.
patent: 5569825 (1996-10-01), Lonberg et al.
patent: 5571894 (1996-11-01), Wels et al.
patent: 5587458 (1996-12-01), King et al.
patent: 5591669 (1997-01-01), Krimpentort et al.
patent: 5641870 (1997-06-01), Rinderknecht et al.
patent: 5648237 (1997-07-01), Carter
patent: 5712374 (1998-01-01), Kuntsmann et al.
patent: 5714586 (1998-02-01), Kuntsmann et al.
patent: 5731168 (1998-03-01), Carter et al.
patent: 5739116 (1998-04-01), Hamann et al.
patent: 5739277 (1998-04-01), Presta et al.
patent: 5767285 (1998-06-01), Hamann et al.
patent: 5770701 (1998-06-01), McGahren et al.
patent: 5770710 (1998-06-01), McGahren et al.
patent: 5773001 (1998-06-01), Hamann et al.
patent: 5789199 (1998-08-01), Joly et al.
patent: 5821337 (1998-10-01), Carter et al.
patent: 5837234 (1998-11-01), Gentile et al.
patent: 5840523 (1998-11-01), Simmons et al.
patent: 5869046 (1999-02-01), Presta et al.
patent: 5877296 (1999-03-01), Hamann et al.
patent: 6331415 (2001-12-01), Cabilly et al.
patent: 6824780 (2004-11-01), Devaux et al.
patent: 2008/0089837 (2008-04-01), Laing et al.
patent: 73657 (1983-03-01), None
patent: 183070 (1986-06-01), None
patent: 244234 (1987-11-01), None
patent: 402226 (1990-12-01), None
patent: 404097 (1990-12-01), None
patent: 0 425 235 (1991-05-01), None
patent: WO 81/01145 (1981-04-01), None
patent: WO 88/07378 (1988-10-01), None
patent: WO 90/13646 (1990-11-01), None
patent: WO 91/00360 (1991-01-01), None
patent: WO 92/20373 (1992-11-01), None
patent: WO 93/08829 (1993-05-01), None
patent: WO 93/11161 (1993-06-01), None
patent: WO 93/16185 (1993-08-01), None
patent: WO 93/21232 (1993-10-01), None
patent: WO 93/21952 (1993-11-01), None
patent: WO 94/04690 (1994-03-01), None
patent: WO 94/11026 (1994-05-01), None
patent: WO 96/07321 (1996-03-01), None
patent: WO 96/16673 (1996-06-01), None
patent: WO 97/17852 (1997-05-01), None
patent: WO 97/38731 (1997-10-01), None
patent: WO 98/02463 (1998-01-01), None
patent: WO 03083061 (2003-10-01), None
Skolnick and Fetrow. From genes to protein structure and function: novel applications of computational approaches in the genomic era. Trends in Biotechnology, 2000. vol. 18, pp. 34-39.
Mac Callum, Martin, and Thornton. Antibody-antigen interactions: contact analysis and binding site topography. Journal of Molecular Biology, 1996. vol. 262, pp. 732-745.
Casset, Roux, Mouchet, Bes, Chardes, Granier, Mani, Pugniere, Laune, Pau, Kaczorek, Lahana, and Rees. A peptide mimetic of an anti-CD4 monoclonal antibody by rational design. Biochemical and Biophysical Research Communications, 2003. vol. 307, pp. 198-205.
Vajdos, Adams, Breece, Presta, De Vos, and Sidhu. Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis. Journal of Molecular Biology, 2002. vol. 320, pp. 415-428.
Wu, Nie, Huse, and Watkins. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues. Journal of Molecular Biology, 1999. vol. 294, pp. 151-162.
Rudikoff, Giusti, Cook, and Scharff. Single amino acid substitution altering antigen-binding specificity. Proceedings of the National Academy of Sciences, 1982. vol. 79, pp. 1979-1983.
De Pascalis, Iwahashi, Tamura, Padlan, Gonzales, Santos, Giuliano, Schuck, Schlom, and Kashmiri. Grafting of abbreviated complementarity determining regions containing specificity determining residues essential for ligand contact to engineer a less immunogenic humanized monoclonal antibody. Journal of Immunology, 2002. vol. 169, pp. 3076-3084.
Holm, Jafari, and Sundstrom. Functional mapping and single chain construction of the anti-cytokeratin 8 monoclonal antibody TS1. Molecular Immunology, 2007. vol. 44, pp. 1075-1084.
Chen, Wiesmann, Fuh, Li, Christinger, Mc Kay, De Vos, and Lowman. Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity matured Fab in complex with antigen. Journal of Molecular Biology, 1999. vol. 293, pp. 865-881.
Altschul et al., “Basic Local Alignment Search Tool”,J. Mol. Biol., 215:403-410 (1990).
Altschul et al., “Gapped BLAST and PSI-BLAST: a new generation of protein database search programs”,Nucl. Acids Res., 25:3389-3402 (1977).
Bird et al., “Single-Chain Amtigen-Binding Proteins”,Science, 242:423-426 (1988).
Bitter et al., “Expression and Secretion Vectors for Yeast”,Methods in Enzymology, 53:516-544 (1987).
Bolton et al., “The Labelling of Proteins to High Specific Radioactivities by Conjugation to a125I-Containing Acylating Agent”,Biochem J., 133:529-539 (1973).
Brennan et al.,Science, “Preparation of Bispecific Antibodies by Chemical Recombination of Monoclonal Immunoglobulin G1Fragments”, 229:81-83 (1985).
Broglie et al., “Light-Regulated Expression of a Pea Ribulose-1,5-Bisposphate Carboxylase Small Subunit Gene in Transformed Plant Cells”,Science, 224:838-843 (1984).
Bruggemann et al., “Designer Mice: The Production of Human Antibody Repertoires in Transgenic Animals”, Year in Immunol., 7:33-40 (1993).
Capel et al., “Heterogeneity of Human IgG Fc Receptors”,Immunomethods, 4:25-34 (1994).
Carlsson et al., “Protein Thiolation and Reversible Protein-Protein Conjugation”,Biochem. J., 173:723-737 (1978).
Caron et al., “Murine and Humanized Constructs of Monoclonal Antibody M195 (Anti-CD33) for the Therapy of Acute Myelogenous Leukimia”,J. Exp. Med., 176:1191-1195 (1992).
Carter et al., “High LevelEscherichia coliExpression and Production of a Bivalent Humanized Antibody Fragment”,Bio./Tech., 10:163-167 (1992).
Chari et al., “Immunoconjugates Containing Novel Maytansinoids: Promising Anticancer Drugs”,Cancer Res., 52:127-131 (1992).
Chothia et al., “Canonical Structures for the Hypervariable Regions of Immunoglobulins”,J. Mol. Biol., 196:901-917 (1987).
Chothia et al., “Conformations of immunoglobulin hypervariable regions”,Nature, 342:877-883 (1989).
Clackson et al., “Making antibody fragments using phage display lib
Elrifi, Esq. Ivor R.
Gussow Anne M.
Miller Katherine J.
Mintz Levin Cohn Ferris Glovsky and Popeo P.C.
Theraclone Sciences, Inc.
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