Apparatus and method for increasing the amplitude of P300 waves

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems

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607 1, 607 2, 607 45, 607 46, 600 26, A61N 136

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active

053424107

ABSTRACT:
A cranial electrotherapy stimulation ("CES") device which generates periodic electrical signals is connected between the forehead and wrist area of a human being in order to affect electrical activity in the brain and thereby decrease the individual's craving for controlled substances such as alcohol and drugs and reduce anxiety, insomnia and depression. A portable, cranial electrical stimulator is preferably mounted adjacent the arm area or worn about the waist of a patient. A first electrode is attached to the forehead of the patient, preferably above the bridge of the nose between the eyes, and a second electrode is attached to the wrist area of one am, preferably at the radial artery. Periodic electrical pulses having a waveform with a current amplitude in the range of 0.1 to 60 mA, a voltage of approximately 40-60 volts, a frequency of approximately 0.1 to 400 Hz, and a pulse width approximately 0.2 to 2 milliseconds at a 20% duty cycle are applied for at least 20 minutes between the forehead and wrist electrode. As a result, electrical activity in the brain is affected, in particular, the amplitude of P300 electrical brain activity is increased. Since decreased P300 activity is associated with increased patient interest in drugs and alcohol, the use of the CES in the is way makes it less likely that the patient will desire such controlled substances.

REFERENCES:
patent: 4509521 (1985-04-01), Barry
patent: 4785813 (1988-11-01), Petrofsky
patent: 5163444 (1992-11-01), Braverman
"The Relax Pak", Neuro Systems Incorp., 1986.
Electrosleep, Lewis and Williams; M.D., 13 Jan. 66, p. 40.
CES Labs 100 Hz User's Manual, 1989, all pages.

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