Recombinant alpha-fetoprotein and method of preparing

Details Recombinant alpha-fetoprotein and method of preparing Recombinant alpha-fetoprotein and method of preparing

2011-03-22

2011-03-22

Bunner, Bridget E (Department: 1647)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S254200, C435S320100, C435S325000, C530S350000

Reexamination Certificate

active

07910327

ABSTRACT:
The invention relates to the microbiological and medical industry, genetic engineering, biotechnology. ASaccharomyces cerevisiaeyeast strain was obtained on the basis of constructing a recombinant plasmid DNA comprising a structural gene of a human alpha-fetoprotein (AFP) under the control of a regulatory promoter, providing the synthesis and production of AFP in a secreted soluble form, this AFP having activity identical or similar to the activity of a human AFP. The obtained recombinant AFP may be used as an active substance for the preparation of therapeutic agents for use in oncology, immunotherapy, cosmetology and also for the diagnosis of cancer and embryonic pathologies.

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