Substituted pyrrolo[2,3-d]pyrimidines for selectively...

Details Substituted pyrrolo[2,3-d]pyrimidines for selectively... Substituted pyrrolo[2,3-d]pyrimidines for selectively...

2011-07-19

2011-07-19

Moore, Susanna (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S280000

Reexamination Certificate

active

07981902

ABSTRACT:
A compound for treating cancer tumors, particularly ovarian cancer tumors, is described, where a fused cyclic pyrimidine having a cancer treating ability is effective to allow selective delivery to a cancerous tumor.

REFERENCES:
patent: 5939420 (1999-08-01), Gangjee
patent: 0438261 (1991-07-01), None
Aleem Gangjee, Yibin Zeng, John J.L McGuire, and Roy L. Kisliuk, Synthesis of Classic Four-Carbon Bridged 5-Substituted Furo [2,3-d] pyrimidine and 6-Substituted Pyrrolo [2,3-d] pyrimid Analogues as Antifolates, J. Medical Chemistry 2005, pp. 5329-5336.

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