Process for preparing and drying solid rasagiline base

Details Process for preparing and drying solid rasagiline base Process for preparing and drying solid rasagiline base

2011-06-28

2011-06-28

Davis, Brian J (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C514S647000

Reexamination Certificate

active

07968749

ABSTRACT:
Disclosed is crystalline R(+)-N-propargyl-l-aminoindan containing water at an amount of less than 0.5% by weight and a pharmaceutical composition comprising the same, and the process for the manufacture and the validation thereof. Also disclosed is a process for the preparation of solid rasagiline base.

REFERENCES:
patent: 5387612 (1995-02-01), Youdim et al.
patent: 5453446 (1995-09-01), Youdim et al.
patent: 5457133 (1995-10-01), Youdim et al.
patent: 5486541 (1996-01-01), Sterling et al.
patent: 5519061 (1996-05-01), Youdim et al.
patent: 5532415 (1996-07-01), Youdim et al.
patent: 5576353 (1996-11-01), Youdim et al.
patent: 5599991 (1997-02-01), Youdim et al.
patent: 5668181 (1997-09-01), Youdim et al.
patent: 5744500 (1998-04-01), Youdim et al.
patent: 5786390 (1998-07-01), Youdim et al.
patent: 5891923 (1999-04-01), Youdim et al.
patent: 6126968 (2000-10-01), Peskin et al.
patent: 6277886 (2001-08-01), Levy et al.
patent: 6316504 (2001-11-01), Youdim et al.
patent: 6462222 (2002-10-01), Chorev et al.
patent: 6630514 (2003-10-01), Youdim et al.
patent: 6956060 (2005-10-01), Youdim et al.
patent: 7396860 (2008-07-01), Blaugrund et al.
patent: 7491847 (2009-02-01), Frenkel
patent: 7547806 (2009-06-01), Frenkel et al.
patent: 7572834 (2009-08-01), Sterling et al.
patent: 7598420 (2009-10-01), Sterling et al.
patent: 7619117 (2009-11-01), Lidor-Hadas et al.
patent: 7750051 (2010-07-01), Frenkel et al.
patent: 7815942 (2010-10-01), Peskin
patent: 7855233 (2010-12-01), Frenkel et al.
patent: 2006/0018957 (2006-01-01), Lerner et al.
patent: 2006/0094783 (2006-05-01), Youdim et al.
patent: 2006/0188581 (2006-08-01), Peskin
patent: 2007/0100001 (2007-05-01), Youdim et al.
patent: 2007/0112217 (2007-05-01), Frenkel
patent: 2007/0232700 (2007-10-01), Blaugrund et al.
patent: 2008/0161408 (2008-07-01), Frenkel et al.
patent: 2009/0062400 (2009-03-01), Oron et al.
patent: 2009/0076160 (2009-03-01), Lendvai et al.
patent: 2009/0111892 (2009-04-01), Patashnick et al.
patent: 2009/0181086 (2009-07-01), Safadi et al.
patent: 2009/0312436 (2009-12-01), Levy et al.
patent: 2010/0008983 (2010-01-01), Safadi et al.
patent: 2010/0010095 (2010-01-01), Frenkel
patent: 2010/0010098 (2010-01-01), Elffrink
patent: 2010/0029987 (2010-02-01), Allegrini et al.
patent: 2010/0137447 (2010-06-01), Lehmann et al.
patent: 2010/0144887 (2010-06-01), Frenkel et al.
patent: 2010/0145101 (2010-06-01), Frenkel et al.
patent: 2010/0168239 (2010-07-01), Poewe
patent: 2010/0189787 (2010-07-01), Safadi et al.
patent: 2010/0189788 (2010-07-01), Safadi et al.
patent: 2010/0189790 (2010-07-01), Safadi et al.
patent: 2010/0189791 (2010-07-01), Frenkel et al.
patent: 2010/0190859 (2010-07-01), Frenkel et al.
patent: 2010/0234636 (2010-09-01), Stahl
patent: WO 2007/101400 (2007-09-01), None
patent: WO 2008/131961 (2008-11-01), None
patent: WO 2009/081148 (2009-07-01), None
patent: WO 2009/122301 (2009-10-01), None
patent: WO 2009/152777 (2009-12-01), None
patent: WO 2010/007181 (2010-01-01), None
patent: WO 2010/013048 (2010-02-01), None
patent: WO 2010/049379 (2010-05-01), None
patent: WO 2010/070090 (2010-06-01), None
patent: WO 2011/003938 (2011-01-01), None
patent: WO 2011/009873 (2011-01-01), None
patent: WO 2011/010324 (2011-01-01), None
Kirk-Othmer Encyclopedia of Chemical Technology, article:Pharmaceuticals, Large-Scale Synthesis, p. 1-12, published online May 13, 2005.
U.S. Appl. No. 12/283,022, filed Sep. 8, 2008, Sterling et al.
U.S. Appl. No. 12/283,107, filed Sep. 8, 2008, Sterling et al.
U.S. Appl. No. 12/283,105, filed Sep. 8, 2008, Sterling et al.
U.S. Appl. No. 12/455,969, filed Jun. 10, 2009, Frenkel et al.
U.S. Appl. No. 12/456,642, filed Jun. 19, 2009, Anton Frenkel.
U.S. Appl. No. 12/456,029, filed Jun. 9, 2009, Safadi et al.
U.S. Appl. No. 12/456,031, filed Jun. 9, 2009, Safadi et al.
U.S. Appl. No. 12/455,976, filed Jun. 9, 2009, Safadi et al.
U.S. Appl. No. 12/456,001, filed Jun. 9, 2009, Safadi et al.
Jul. 8, 2009 Office Action issued in U.S. Appl. No. 12/002,082.
May 2, 2008 International Search Report for PCT International Application No. PCT/US07/025583.
Jun. 16, 2009 International Preliminary Report on Patentability and the Written Opinion of the International Searching Authority for Internat'l Appln. No. PCT/US07/025583.
U.S. Appl. No. 12/655,827, filed Jan. 8, 2010 (Frenkel, et al.) (including specification and pending claim set).
U.S. Appl. No. 12/655,828, filed Jan. 8, 2010 (Frenkel, et al.) (including specification and pending claim set).
U.S. Appl. No. 12/901,281, filed Oct. 8, 2010 (Lorenzl).
U.S. Appl. No. 12/974,769, filed Dec. 21, 2010 (Frenkel et al.).
Oct. 5, 2009 International Search Report for International Application No. PCT/US2009/03670.
Dec. 21, 2010 International Preliminary Report on Patentability and Written Opinion of the International Searching Authority for Application No. PCT/US2009/03670.

Affiliated with

Also associated with

Rating

Process for preparing and drying solid rasagiline base does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing and drying solid rasagiline base, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing and drying solid rasagiline base will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2705317