HIV integrase inhibitors

Details HIV integrase inhibitors HIV integrase inhibitors

2011-06-28

2011-06-28

Ward, Paul V. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S094000

Reexamination Certificate

active

07968564

ABSTRACT:
Tricyclic compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication:wherein bond a, ring A, R1, R2and R3are defined herein. The compounds are useful for the prophylaxis or treatment of infection by HIV and the prophylaxis, treatment, or delay in the onset of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

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