Process for phenylacetic acid derivatives

Details Process for phenylacetic acid derivatives Process for phenylacetic acid derivatives

2011-03-15

2011-03-15

Saeed, Kamal A (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C564S413000

Reexamination Certificate

active

07906677

ABSTRACT:
A process for the production of a compound of Formula I, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable prodrug ester thereof,comprising cleaving a lactam of formula IIwherein the symbols are as defined, with a base; and precursors therefor and processes for the preparation of the precursors. The compounds of Formula I are pharmaceutically active compounds which are selective inhibitors of Cyclooxygenase II.

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