Carboxylic acid compound, use thereof, and process for...

Details Carboxylic acid compound, use thereof, and process for... Carboxylic acid compound, use thereof, and process for...

2011-07-26

2011-07-26

Sullivan, Daniel (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C562S586000, C568S683000

Reexamination Certificate

active

07985877

ABSTRACT:
The present invention provides a process for producing 1,1,1,3,3,3-hexafluoro-2-methoxypropane, wherein a novel compound, 2-methoxy-2-trifluoromethyl-3,3,3-trifluoropropionic acid or a salt thereof is decarboxylated, or wherein an olefin compound represented by chemical formula (4): CF2═C(CF3)(OCH3) is reacted with a fluorinating agent; and a process for producing 2-methoxy-2-trifluoromethyl-3,3,3-trifluoropropionic acid or a salt thereof by reacting a hydroxycarboxylic ester with a methylating agent and then hydrolyzing the reaction product, or hydrolyzing the hydroxycarboxylic ester and then reacting the resulting product with a methylating agent.In accordance with the invention, 1,1,1,3,3,3-hexafluoro-2-methoxypropane, which is useful as a raw material for, for example, the anesthetic Sevoflurane, can be produced efficiently and at low cost.

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Supplementary European Search Report dated Apr. 21, 2010 issued in European Application No. 07 74 4472 corresponding to present US application.
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