Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fusion protein or fusion polypeptide
Reexamination Certificate
2011-03-29
2011-03-29
Chen, Shin-Lin (Department: 1632)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fusion protein or fusion polypeptide
C530S350000, C536S023100, C435S455000, C435S463000
Reexamination Certificate
active
07914796
ABSTRACT:
Disclosed herein are engineered cleavage half-domains; fusion polypeptides comprising these engineered cleavage half-domains; polynucleotides encoding the engineered cleavage half-domains and fusion proteins; and cells comprising these polynucleotides and/or fusion proteins. Also described are methods of using these polypeptides and polynucleotides, for example for targeted cleavage of a genomic sequence.
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Cost Gregory J.
Holmes Michael C.
Miller Jeffrey C.
Chen Shin-Lin
Pasternak Dahna S.
Robins & Pasternak LLP
Sangamo Biosciences, Inc.
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