Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Reexamination Certificate
2011-06-21
2011-06-21
Winakur, Eric F (Department: 3777)
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
C600S310000
Reexamination Certificate
active
07966060
ABSTRACT:
For determining autofluorescence of a clinically normal skin issue (7) of a patient, the tissue (7) is irradiated with electromagnetic radiation. An amount of fluorescent radiation emitted by the tissue (7) in response to the irradiation is measured and, in response thereto, a signal is generated which represents a determined autofluorescence in agreement with the measured amount of electromagnetic radiation. Because the tissue (7) is skin tissue (7) in vivo and irradiation is performed noninvasively, a method which is very simple to apply for determining autofluorescence is obtained. An apparatus especially adapted for use in this method is also described.
REFERENCES:
patent: 4773722 (1988-09-01), Perino
patent: 5279297 (1994-01-01), Wilson et al.
patent: 5452723 (1995-09-01), Wu et al.
patent: 5601079 (1997-02-01), Wong et al.
patent: 5755226 (1998-05-01), Carim et al.
patent: 5851181 (1998-12-01), Talmor
patent: 6436127 (2002-08-01), Anderson et al.
patent: 6505059 (2003-01-01), Kollias et al.
patent: 6721582 (2004-04-01), Trepagnier et al.
patent: 2006/0195022 (2006-08-01), Trepagnier et al.
patent: 37 18202 (1988-11-01), None
patent: 0 003 015 (1979-07-01), None
patent: 97/15226 (1997-05-01), None
M.H. Dominiczak et al.,Increased Collagen-Linked Fluorescence in Skin of Young Patients With Type 1 Diabetes Mellitus, Diabetes Care, May 1990, vol. 13, No. 5, pp. 468-472.
P.J. Beisswenger et al.,Formation of Immunochemical Advanced Glycosylation End Products Precedes and Correlates With Early Manifestations of Renal and Retinal Disease in Diabetes, Diabetes, Jul. 1995, vol. 44, pp. 824-829.
M. Brownlee,Glycation and Diabetic Complications, Diabetes, Jun. 1994, vol. 43, pp. 836-841.
D.R. Sell et al.,Pentosidine Formation in Skin Correlates With Severity of Complications in Individuals With Long-Standing IDDM, Diabetes, Oct. 1992, vol. 41, pp. 1286-1291.
R.H. Nagaraj et al.,Evidence of a Glycemic Threshold for the Formation fo Pentosidine in Diabetic Dog Lens but Not in Collagen, Diabetes, May 1996, vol. 45, pp. 587-594.
R.H. Mayer et al.,Measurement of the fluorescence lifetime in scattering media by frequency-domain photon migration, Applied Optics, Aug. 1999, vol. 38, No. 22, pp. 4930-4938.
Graaff Reindert
Jager Jan
Oomen Petrus Hendricus N.
Smit Andries Jan
Diagnoptics Holding B.V.
Pearne & Gordon LLP
Winakur Eric F
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