Process for producing 3-O-demethylfortimicins

Details Process for producing 3-O-demethylfortimicins Process for producing 3-O-demethylfortimicins

1979-03-29

1980-10-28

Brown, JohnnieR.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 18, 424180, C07H 1522

Patent

active

042308488

ABSTRACT:
An improved process for producing 3-O-demethylfortimicins comprising the steps of reacting the fortimicin to be 3-O-demethylated with a borontrihalide and recovering the 3-O-demethylfortimicin from the reaction mixture.

REFERENCES:
patent: 4124756 (1978-11-01), Martin et al.
Pigman, "The Carbohydrates", 1957, Academic Press, Inc., New York, N.Y., p. 368.
Noller, "Chemistry of Organic Compounds", 1965, W. B. Saunders Co., Philadelphia, Pa., pp. 161, 395 and 846.

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