High-viscosity eye lotions

Details High-viscosity eye lotions High-viscosity eye lotions

1979-04-26

1980-10-28

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

A61K 3174

Patent

active

042306906

ABSTRACT:
The invention presents a high-viscosity eye lotion with which lasting curve effects can be obtained with no feeling of foreign bodies to the eye as in the conventional eye salves used in treating eyes.
The high-viscosity eye lotion of the invention comprises a swollen hydrated gel of a crosslinked polyvinyl alcohol and an eye-disease curative active ingredient contained therein. It is prepared by irradiating an aqueous solution of a polyvinyl alcohol with an ionizing radiation to such an extent that the polyvinyl alcohol is crosslinked to give a hydrated gel with an equilibrium swelling ratio in the range from 70 to 100 by weight and then dipping the hydrated gel in an aqueous solution of the eye-disease curative active agent.

REFERENCES:
patent: 3639576 (1972-02-01), Kaspar et al.
patent: 3863633 (1975-02-01), Ryde et al.
patent: 3868445 (1975-02-01), Ryde et al.
patent: 4003991 (1977-01-01), Krohn et al.
Symposium on Ocular Therapy 9, 1-16 (1977), Maichuk.

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