Pharmaceutical compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Reexamination Certificate

active

07956065

ABSTRACT:
This application describes method of treating dementia and cognitive deficits associated with dementia that involve administration of dihydrotetrabenazine, and isomers and/or pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 2830993 (1958-04-01), Brossi et al.
patent: 2843591 (1958-07-01), Brossi et al.
patent: 2954382 (1960-09-01), Osbond
patent: 3009918 (1961-11-01), Openshaw et al.
patent: 3045021 (1962-07-01), Brossi
patent: 3053845 (1962-09-01), Tretter
patent: 3079395 (1963-02-01), Brossi et al.
patent: 3095419 (1963-06-01), Tretter
patent: 3105079 (1963-09-01), Tretter
patent: 3123609 (1964-03-01), Openshaw et al.
patent: 3132147 (1964-05-01), Schopf et al.
patent: 3159638 (1964-12-01), Ritchie et al.
patent: 3209005 (1965-09-01), Brossi et al.
patent: 3314966 (1967-04-01), Brossi et al.
patent: 3342825 (1967-09-01), Openshaw et al.
patent: 3375254 (1968-03-01), Openshaw et al.
patent: 3390152 (1968-06-01), Harnden
patent: 3634431 (1972-01-01), Van Dyke
patent: 3635986 (1972-01-01), Van Dyke
patent: 4076820 (1978-02-01), Archibald et al.
patent: 4102886 (1978-07-01), Szantay et al.
patent: 4133812 (1979-01-01), Szaantay et al.
patent: 4304913 (1981-12-01), Havera et al.
patent: 4353656 (1982-10-01), Sohl et al.
patent: 4778054 (1988-10-01), Newell et al.
patent: 4811731 (1989-03-01), Newell et al.
patent: 5035237 (1991-07-01), Newell et al.
patent: 5590645 (1997-01-01), Davies et al.
patent: 5860419 (1999-01-01), Davies et al.
patent: 5873360 (1999-02-01), Davies et al.
patent: 6087376 (2000-07-01), Crooks et al.
patent: 6462069 (2002-10-01), Reich et al.
patent: 6482986 (2002-11-01), Boigegrain et al.
patent: 6632666 (2003-10-01), Baust et al.
patent: 2005/0064034 (2005-03-01), Li et al.
patent: 2006/0173011 (2006-08-01), Shin et al.
patent: 2008/0108645 (2008-05-01), Tridgett et al.
patent: 2008/0319000 (2008-12-01), Tridgett
patent: 2009/0275605 (2009-11-01), Duffield et al.
patent: 2010/0055133 (2010-03-01), Duffield et al.
patent: 2010/0063086 (2010-03-01), Nichols
patent: 2010/0087475 (2010-04-01), Duffield et al.
patent: 2010/0087476 (2010-04-01), Duffield et al.
patent: 2011/0053866 (2011-03-01), Duffield et al.
patent: 0069715 (1983-01-01), None
patent: 0839805 (1998-06-01), None
patent: 2064336 (1981-06-01), None
patent: 2129691 (1984-05-01), None
patent: 2169265 (1986-07-01), None
patent: 2178965 (1987-02-01), None
patent: 2242134 (1991-09-01), None
patent: 2410947 (2005-08-01), None
patent: 2463452 (2010-03-01), None
patent: WO-2005077946 (2005-08-01), None
patent: WO-2006069030 (2006-06-01), None
patent: WO-2007007105 (2007-01-01), None
patent: WO-2007017643 (2007-02-01), None
patent: WO-2007017654 (2007-02-01), None
patent: WO-2008079404 (2008-07-01), None
patent: WO2009150474 (2009-12-01), None
patent: WO2011019956 (2011-02-01), None
“U.S. Appl. No. 10/597,803, Final Office Action mailed Oct. 27, 2009”, 22 Pgs.
“U.S. Appl. No. 10/597,803, Response filed Jul. 29, 2009 to Non Final Office Action mailed Jan. 29, 2009”, 26 pgs.
“European Application Serial No. 05708289.3, Response filed Sep. 17, 2007”, 8 pgs.
“International Application Serial No. PCT/GB2005/000464, International Search Report mailed Jun. 10, 2005”, 4 pgs.
“International Application Serial No. PCT/GB2005/000464, Preliminary Report on Patentability mailed Aug. 14, 2006”, 9 pgs.
“International Application Serial No. PCT/GB2005/000464, Written Opinion mailed Jun. 10, 2005”, 8 pgs.
“SYNKEM European DMF for Tetrabenazine”, (Sep. 2005), 145 pgs.
Albin, R. L, et al., “Increased ventral striatal monoaminergic innervation in Tourette syndrome”, Neurology, 61(3), (Aug. 12, 2003), 310-5.
Aranda, G., et al., “Synthesis and biological activity of iodinated and photosensitive derivatives of tetrabenazine”, European Journal of Medicinal Chemistry, 25(4), (May 1990), 369-374.
Balkissoon, Ronald, “Asthma Overview”, Primary Care: Clinics in Office Practice, vol. 35, Iss 1, (Mar. 2008), 41-60.
Berge, Stephen M, et al., “Pharmaceutical Salts”, J. Pharm Sci., 66(1), (1977), 1-19.
Bohnen, N. I, et al., “Decreased striatal monoaminergic terminals in Huntington disease”, Neurology, 54(9), (May 9, 2000), 1753-9.
Brossi, et al., “Syntheseversuche in der Emetin-Reihe 3. Mitteilung: 2-Hydroxy-hydrobenzo[a]chinolizine”, Helvetica Chimica Acta vol. XLI, No. 193, (1958), 1793-1806.
Brossi, et al., “Syntheseversuche in der Emetin-Reihe 4. Mitteilung: Racemisches 2-Dehydro-emetin”, Helvetica Chimica Acta vol. 42, (1959), 772-788.
Brossi, et al., “Syntheseversuche in der Emetin-Reihe 7. Mitteilung: Abbau und Synthese substituierter 2-Oxo-hydrobenzo[a]chinolizine”, Helvetica Chimica Acta, vol. XLIII, No. 77, (1960), 583-593.
Brossi, et al., “Syntheseversuche in der Emetinreihe 9. Mitteilung: Die Absolute Konfiguration von (-)-2-Dehydro-emetin”, Helvetica Chimica Acta, vol. XLV No. 257, (1962), 2219-2226.
Brossi, et al., “Synthetic Experiments in the Emetine Series”, Helv. Chim. Acta. vol. XLI, No. 193, (1958), 119-139.
Brossi, A., et al., “Synthese und absolute Konfiguration von (-)-2-Dehydroemetin”, Experentia, (1962), 211-212.
Brossi, A., et al., “Syntheseversuche in der Emetin-Reihe 2. Mitteilung: Neue Reaktionen mit 3,4-dihydro-isochinolinen”, Chimia, 12, (1958), 114-115.
Brossi, A., et al., “Syntheseversuche in der Emetinreihe 8. Mitteilung Rac. Emetin-Isomere der 2,3-cis-Reihe”, Helvetica Chimica Acta, 45(6), (1962), 1899-1907.
Brossi, V. A, et al., “Synthesen in der Emetin-Reihe”, Arzneimittel Forschung, 15, (1965), 670-674.
Bruderer, et al., “Synthesen in der Emetin-Reihe 11. Mitteliung: 2-Aryisubstituierte Hydrobenzo[a]chinolizine”, Helvetica Chimica Acta, 47(203), (1964), 1852-1860.
Canney, et al., “Amino- and Amido-Tetrabenazine Derivatives: Synthesis and Evaluation as Potential Ligands for the Vesicular Monoamine Transporter”, Nucl. Med. Biol. 22, (1995), 527-535.
Dasilva, et al., “Characterization of [11C]Tetrabenazine as an in Vivo Radioligand for the Vesicular Monoamine Transporter”, Nucl. Med. Biol vol. 21, No. 2, (1994), 151-156.
Dasilva, et al., “In Vivo Binding of [11C]Tetrabenazine to Vesicular Monoamine Transporters in Mouse Brain”, Life Sciences vol. 51, (1992), 593-600.
Dasilva, et al., “In Vivo Imagine of Monoaminergic Nerve Terminals in Mormal and MPTP-Lesioned Primate Brain Using Positron Emission Tomography (PET) and [11C]Tetrabenazine”, Synapse 14, (1993), 128-131.
Dasilva, J. N, et al., “Synthesis of a [11C]methoxy derivative of alpha-dihydrotetrabenazine: a radioligand for studying the vesicular monoamine transporter.”, Appl Radiat Isot., 44(12), (Dec. 1993), 1487-9.
De Silva, Jean, et al., “Synthesis of [11C]Tetrabenazine, a Vesicular Monoamine Uptake Inhibitor, for PET Imaging Studies”, Appl. Radiat. Isot. vol. 44: No. 4, (1993), 673-676.
Flack, et al., “Reporting and evaluating absolute-structure and absolute-configuration determinations”, Journal of Applied Crystallography 33, (2000), 1143-1148.
Frey, et al., “Imagine of Monoaminergic and Cholinergic Vesicular Transporters in the Brain”, Advances in Pharmacology vol. 42, (1998), 269-272.
Frey, et al., “Presynaptic Monoaminergic Vesicles in Parkinsons Disease and Normal Aging”, Ann. Neurol. 40, (1996), 873-884.
Gerecke, M, et al., “Syntheseversuche in der Emetin-Reihe 10. Mitteilung: Zur Oxydation von 2-Dehydro-emetin-Verbindungen mit Quecksilber(II)-acetat”, Helvetica Chimica Acta, vol. 47 No. 121, (1964), 1117-1123.
Gilman, et al., “Decreased Striatal Monoaminergic Terminals in Olivopontocerebellar Atrophy and Multiple System Atrophy Demonstrated with Positron Emission Tomography”, Ann. Neurol 40, (1996), 885-892.
Jankovic, J., et al., “Long-term effects of tetrabenazin

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