Surgery – Controlled release therapeutic device or system
Reexamination Certificate
2011-04-05
2011-04-05
Lucchesi, Nicholas D (Department: 3763)
Surgery
Controlled release therapeutic device or system
C604S093010
Reexamination Certificate
active
07918842
ABSTRACT:
Implantable medical devices are provided for controlled release of drugs. In one embodiment, the device comprises a support structure; two or more discrete reservoirs provided in spaced positions across at least one surface of the support structure; and a release system loaded in each of the reservoirs, the release system including drug molecules dispersed in a degradable matrix material, wherein release of the drug molecules from the reservoir is controlled by in vivo disintegration of the matrix material. In another embodiment, the device comprises a support structure; two or more discrete reservoirs provided in spaced positions across at least one surface of the support structure; and a release system loaded in each of the reservoirs, the release system including drug molecules dispersed in a non-degradable matrix material, wherein release of the drug molecules from the reservoir is controlled by in vivo diffusion of the drug molecules from the matrix material.
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Cima Michael J.
Langer Robert S.
Santini, Jr. John T.
Lucchesi Nicholas D
Massachusetts Institute of Technology
Sutherland & Asbill & Brennan LLP
Vu Quynh-Nhu H
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