Pyridine derivatives and their use in the treatment of...

Details Pyridine derivatives and their use in the treatment of... Pyridine derivatives and their use in the treatment of...

2011-04-05

2011-04-05

Habte, Kahsay T (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S105000

Reexamination Certificate

active

07919491

ABSTRACT:
A pyridine derivative novel compounds of formula (I) or a pharmaceuticallyacceptable salt thereof where all variables are defined herein. The compounds are useful in the treatment of psychotic disorders.

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Natsugari, H. et al.; Novel, Potent and orally active substance P Antagonists: Synthesis and Antagonist Activity of N-Benzylcarboxamide Derivatives of Pyrido [3,4-b] pyridine; Journal of Medicinal Chemistry; 1995; 38; 3106-3120; American Chemical Society.
Ikeura, Y., et al.; Potent NK1 Receptor Antagonists: Synthesis and Antagonistic Activity of various Heterocycles with anN-[3,5-Bis(trifluoremethyl)benzyl]-N-methylcarbamoyl Substituent; Chem. Pharm. Bull.; 1997; 45/10; 1642-1652; Pharmaceutical Society of Japan.

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