System for concentrating and analyzing particles suspended...

Details System for concentrating and analyzing particles suspended... System for concentrating and analyzing particles suspended...

2011-04-26

2011-04-26

Noguerola, Alex (Department: 1795)

Chemistry: electrical and wave energy

Apparatus

Electrophoretic or electro-osmotic apparatus

C204S600000, C204S601000, C204S547000, C204S451000, C422S091000, C422S105000

Reexamination Certificate

active

07931792

ABSTRACT:
Disclosed is a device for separating and concentrating particles suspended in a fluid stream by using dielectrophoresis (DEP) to trap and/or deflect those particles as they migrate through a fluid channel. The method uses fluid channels designed to constrain a liquid flowing through it to uniform electrokinetic flow velocities. This behavior is achieved by connecting deep and shallow sections of channels, with the channel depth varying abruptly along an interface. By careful design of abrupt changes in specific permeability at the interface, an abrupt and spatially uniform change in electrokinetic force can be selected. Because these abrupt interfaces also cause a sharp gradient in applied electric fields, a DEP force also can be established along the interface. Depending on the complex conductivity of the suspended particles and the immersion liquid, the DEP force can controllably complement or oppose the local electrokinetic force transporting the fluid through the channel allowing for manipulation of particles suspended in the transporting liquid.

REFERENCES:
patent: 6186660 (2001-02-01), Kopf-Sill et al.
patent: 7534334 (2009-05-01), Fiechtner et al.

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