Inotropic orthorhythmic cardiac stimulator

Details Inotropic orthorhythmic cardiac stimulator Inotropic orthorhythmic cardiac stimulator

2011-03-29

2011-03-29

Layno, Carl H (Department: 3766)

Surgery: light, thermal, and electrical application

Light, thermal, and electrical application

Electrical therapeutic systems

Reexamination Certificate

active

07917211

ABSTRACT:
Programmable and implantable automatic heart stimulation device (OIST) for controlling the heart, accompanied by a marked increase in the contractility of the myocardial cells on each beat produced by an optimized post-extrasystolic potentiation effect. The OIST does not cause lasting fatigue of the myocardium, markedly increases the coronary rate instantaneously and durably, causes dilatation of the walls to regress and opposes thromboses and arrhythmia. The OIST creates a genetic involution of the pathological process either by the mere effect of the mechanosensitivity of specific genetic expressions or by the addition of partial autologous cell dedifferentiation, obtained by original genetic manipulation which induces physiological an anatomical regeneration. This method also allows physiological auto-contractile living arterial stents, in particular coronary stents to be created, as well as the grafting of dedifferentiated myocardial cells.

REFERENCES:
patent: 3857399 (1974-12-01), Zacouto
patent: 3939844 (1976-02-01), Pequignot
patent: 4052911 (1977-10-01), Feldstein
patent: 4280502 (1981-07-01), Baker
patent: 5213098 (1993-05-01), Bennett
patent: 5305745 (1994-04-01), Zacouto
patent: 5306293 (1994-04-01), Zacouto
patent: 2003/0074029 (2003-04-01), Deno
patent: 1237702 (1960-06-01), None
patent: WO 02/53026 (2002-07-01), None
patent: WO 03/020364 (2003-03-01), None
PCT International Search Report as issued in International Application No. FR2004/002767 mailed Jun. 17, 2005.
Wayne Cooper, Circulation, vol. 88, No. 6, 2962, Dec. 1993.
F. Zacouto, LaNouvelle Pressue Nedicale, 1974, vol. 3, No. 22, p. 1448.
Dtsch. Gesellsch. Kreislauff, 29 Congress, pp. 255-261, 1963, Steinkopff Verlag Darmstadt.
K. Theissen et al., Klin. Wschr. 52, 1082-1084, 1974, Springer-Verlag.
Roy et al., Nat. Biotechnol. Mar. 22, 2004(3):297-305 (Epub. Feb. 15, 2004) (Abstract Only).
N. Mirochnik et al., Arch. Mal. Coeur, Paris, 93, 10 Cot. 2000 (Abstract Only).

Affiliated with

Also associated with

Rating

Inotropic orthorhythmic cardiac stimulator does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Inotropic orthorhythmic cardiac stimulator, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inotropic orthorhythmic cardiac stimulator will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2660132