Method for preparing medetomidine and its salts

Details Method for preparing medetomidine and its salts Method for preparing medetomidine and its salts

2011-03-08

2011-03-08

Kosack, Joseph R (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S396000

Reexamination Certificate

active

07902377

ABSTRACT:
The invention provides an improved, highly efficient method for preparing Medetomidine, and its salts, in particular its pharmaceutically acceptable salts. The method utilizes the high reactivity of halogenated imidazoles towards transmetalation with Grignard reagents and the subsequent reaction with 2,3-dimethylbenzaldehyde.

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