Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2011-04-26
2011-04-26
Belyavskyi, Michail A (Department: 1644)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S388100, C530S388150
Reexamination Certificate
active
07932361
ABSTRACT:
The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
REFERENCES:
patent: 4923813 (1990-05-01), Hecht et al.
patent: 5011912 (1991-04-01), Hopp et al.
patent: 5194596 (1993-03-01), Tischer et al.
patent: 5350836 (1994-09-01), Kopchick et al.
patent: 5536637 (1996-07-01), Jacobs
patent: 5670367 (1997-09-01), Dorner et al.
patent: 5728536 (1998-03-01), Ihle et al.
patent: 5821053 (1998-10-01), Auron et al.
patent: 5849498 (1998-12-01), Bandman et al.
patent: 6030780 (2000-02-01), Vinkemeier et al.
patent: 6312922 (2001-11-01), Edwards et al.
patent: 6534631 (2003-03-01), Ruben et al.
patent: 6812339 (2004-11-01), Venter et al.
patent: 7091315 (2006-08-01), Ruben et al.
patent: 7368531 (2008-05-01), Rosen et al.
patent: 7393663 (2008-07-01), Edwards et al.
patent: 7411051 (2008-08-01), Rosen et al.
patent: 2003/0017500 (2003-01-01), Ruben et al.
patent: 2003/0040088 (2003-02-01), Ruben et al.
patent: 2005/0155089 (2005-07-01), Lal et al.
patent: 2006/0263774 (2006-11-01), Clark et al.
patent: 2007/0224663 (2007-09-01), Rosen et al.
patent: WO-91/04328 (1991-04-01), None
patent: WO-97/07198 (1997-02-01), None
patent: WO-00/00610 (2000-01-01), None
patent: WO-00/04140 (2000-01-01), None
patent: WO-00/73348 (2000-12-01), None
patent: WO-01/40466 (2001-06-01), None
patent: WO-01/51504 (2001-07-01), None
Bost et al. Immunol. Invest. 1988; 17:577-586.
Bendayan J. Histochem. Cytochem. 1995; 43: 881-886.
U.S. Appl. No. 09/912,293, Rosen et al.
Setni et al.,Human Immunology, vol. 46, pp. 69-81, 1996.
Geneseq Accession No. AAY11487 (Feb. 11, 1999).
“Toward a complete human genome sequence”,Genome Res., 8(11):1097-2108 (Nov. 1998)—Abstract only.
Genbank Accession No. AC005081 (Jun. 12, 1998).
Auffray et al., Genbank Accession No. Z39117 (Oct. 31, 1994).
Genbank Accession No. AA807717 (Feb. 18, 1998).
Hillier et al., Genbank Accession No. N48658 (Feb. 14, 1996).
Sohn et al., Genbank Accession No. T25945 (Mar. 10, 1998).
Adams et al., Genbank Accession No. T30849 (Sep. 6, 1995).
Genbank Accession No. AA731435 (Jan. 23, 1998).
Genbank Accession No. AA810638 (Feb. 13, 1998).
Hillier et al., Genbank Accession No. AA166766 (Dec. 19, 1996).
Genbank Accession No. AA975334 (May 22, 1998).
Hillier et al., Genbank Accession No. N48728 (Feb. 14, 1996).
Genbank Accession No. AA648496 (Oct. 29, 1997).
Adams et al., Genbank Accession No. AA361096 (Apr. 21, 1997).
Genbank Accession No. AA594614 (Sep. 18, 1997).
Hillier et al., Genbank Accession No. T61448 (Feb. 13, 1995).
Hillier et al., Genbank Accession No. N34423 (Jan. 16, 1996).
Genbank Accession No. AA765412 (Feb. 19, 1998).
Hillier et al., Genbank Accession No. H23560 (Jul. 6, 1995).
Hillier et al., Genbank Accession No. AA722908 (Jan. 2, 1998).
Hillier et al., Genbank Accession No. W58075 (Oct. 15, 1996).
Hillier et al., Genbank Accession No. AA723128 (Jan. 2, 1998).
Genbank Accession No. AA633095 (Oct. 31, 1997).
Hillier et al., Genbank Accession No. W57991 (Oct. 15, 1996).
Genbank Accession No. AA604586 (Sep. 29, 1997).
Genbank Accession No. AA827120 (Mar. 5, 1998).
Genbank Accession No. AA811488 (Feb. 19, 1998).
Genbank Accession No. AA593214 (Sep. 25, 1997).
GIBCO BRL, “Random Printers DNA Labeling System”, GIBCO BRL Catalogue and Reference Guide, Life Technologies, Inc. Gaithersburg, MD, USA, p. 404 (1990).
Watson et al., “Methods of Creating Recombinant DNA Molecules”, Recombinant DNA, Chapter 5, pp. 63-77, Scientific American Books (1994).
Ikeda et al., “Epitope Mapping of Anti-recA Protein IgGs by Region Specified Polymerase Chain Reaction Mutagenesis”,J. Biol. Chem., 267(9):6291-6296 (1992).
Stuurman et al., “Interphase phosphorylation of theDrosophilanuclear lamin: site-mapping using a monoclonal antibody”,J. Cell Science, 108:3137-3144 (1995).
Everett et al., “Pendred syndrome is caused by mutations in a putative sphate transporter gene (PDS),”Nat. Genet., 17:411-422 (Dec. 1997).
Scott et al., “The pendred syndrome gene encodes a chloride-iodide transport protein,”Nat. Genet., 21:440-443 (Apr. 1999).
Duan et al., “Characterization of the VHL tumor suppressor gene product: Localization, complex formation, and the effect of natural inactivating mutations,”Proc. Natl, Acad. Sci, USA, 92:6459-6463 (Jul. 1995).
Database PubMed, ID No. 10929036, De Vos et al., “JAK2 Tyrosine Kinase Inhibitor Tyrphostine AG490 Downregulates the Mitogen-activated Protein Kinase (MAPK) and Signal Transducer and Activator of Transcription (STAT) Pathways and Induces Aposptosis in Myeloma Cells,”J. Haematol. 109(4):823-828 (Jun. 2000), see Abstract.
Database PubMed ID No. 10602002, Puthier et al., “IL-6 Up-regulates mcl-1 in Human Myeloma Cells Ethrough JAK/STAT Rather than ras/MAP Kinase Pathway,”Eur. J.Immunol., 29(12):3945-3950 (Dec. 1999), see Abstract.
Database PubMed ID No. 9815779, Ogata et al., “Blockade of Mitogen-activated Protein Kinase Cascade Signaling in Interleukin 6-independCent Multiple Myeloma Cells,”Clin. Cancer Res., 3(6):1017-1022 (Jun. 1997), see Abstract.
Bost et al., “Antibodies Against a Peptide Sequence Within the HIV Envelope Protein Crossreacts With Human Interleukin-2,”Immunol. Invest., 17(6&7):577-586 (1988).
Bendayan, M., “Possibilities of False Immunocytochemical Results Generated by the Use of Monoclonal Antibodies: The Example of the Anti-proinsulin Antibody,”J. Histochem. Cytochem., 43(9):881-886 (1995).
Koonpaew et al., “The importance of three membrane-distal tyrosines in the adaptor protein NTAL/LAB,”J. Biol. Chem., (Jan. 13, 2004) [Epub ahead of print].
Lindquist et al., “Transmembrane adapters: attractants for cytoplasmic effectors,”Immunol. Rev., 191:165-182 (Feb. 2003).
Janssen et al., “LAB: a new membrane-associated adaptor molecule in B cell activation,”Nat. Immunol., 4(2):117-123 (Feb. 2003).
Brdicka et al., “Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling,”J. Exp. Med., 196(12):1617-1626 (Dec. 16, 2002).
International Search Report for PCT/US99/15849, mailed Oct. 21, 1999.
International Search Report for PCT/US01/00911, mailed Apr. 18, 2001.
Database NCBI, Accession No. AC012267,Homo sapiensClone, May 26, 2000.
International Search Report for PCT/US01/29871, mailed Jun. 26, 2003.
Anisowicz et al., “A Novel Protease Homolog Differentially Expressed in Breast and Ovarian Cancer”Mol. Med. 2(5):624-636 (Sep. 1996).
Barton et al., “Protein sequence alignment and database scanning”, Protein Structure Prediction, A Practical Approach, IRL Press at Oxford University Press, Oxford, UK, pp. 31-63 (1996).
Clark et al. “The potential role for prolactin-inducible protein (PIP) as a marker of human breast cancer micrometastasis”Brit. J. Cancer81(6):1002-1008 (1999).
desJardins et al, “Prediction of enzyme classification from protein sequence without the use of sequence similarity,”Amer. Assoc. Artific. Intell. pp. 92-99 (1997).
Everett et al., “Pendred Syndrome is Caused by Mutations in a Putative Sulphate Transporter Gene (PDS),”Nat. Genet. 17:411-422 (1997).
Ferrari et al., “Prospective Analysis of Prostate-Specific Markers in Pelvic Lymph Nodes of Patients With High-Risk Prostate Cancer”J. Natl. Cancer Inst. 89(20):1498-1504 (Oct. 15, 1997).
George et al., “Current Methods in Sequence Comparison and Analysis”, Macromolecular Sequencing and Synthesis, Selected Methods and Applications, D.H. Schlesinger (ed.) Alan R. Liss, Inc., New Yo
Endress Gregory A.
Rosen Craig A.
Ruben Steven M.
Belyavskyi Michail A
Human Genome Sciences Inc.
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