Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2011-02-01
2011-02-01
Yu, Melanie (Department: 1641)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S007100, C435S283100, C436S518000, C436S524000, C436S525000, C977S700000, C977S702000, C977S704000, C977S705000, C977S720000
Reexamination Certificate
active
07879594
ABSTRACT:
The present invention relates to a method for detecting a target biomolecule in a sample comprising a plurality of biomolecules, whereby the target biomolecule is provided with a tag, said tag comprising a catalytic active moiety which catalyses a reaction yielding an insoluble reaction product which precipitates on flexible electrically conductive nanoelectrodes. The precipitation onto said nanoelectrodes causes a change in their electroconductivity which is accessible to electroanalytical methods. The invention relates further to a biochip comprising a solid support with nanoelectrodes attached thereto and probe molecules bound to all or to a plurality of said nanoelectrodes which may be the same or different, a segment of said probe molecules being able to interact specifically with a segment of the target biomolecules.
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Dupont-Filliard Agnes
Mandrand Bernard
Biomerieux
Millen White Zelano & Branigan P.C.
Yu Melanie
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