Quantification of analytes using accelerator mass spectrometry

Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,...

Reexamination Certificate

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C436S056000, C436S057000, C436S063000, C436S161000, C436S173000, C436S174000, C436S175000, C436S177000, C422S071000, C250S281000, C250S282000, C250S303000, C073S001010, C073S001020

Reexamination Certificate

active

07985589

ABSTRACT:
The invention provides a calibrating method for use in a method of determining the quantity of an analyte labeled with an accelerator mass spectrometry (AMS) isotope in a test sample. The samples can include, for example, urine, faeces, plasma or blood. The analyte can be, for example, a drug or metabolite of a drug.

REFERENCES:
patent: 0714040.3 (2007-07-01), None
patent: WO95/04369 (1995-02-01), None
patent: WO2004/077061 (2004-09-01), None
patent: WO2006/092584 (2006-09-01), None
patent: WO2008/064138 (2008-05-01), None
Lappin et al. Analytical Biochemistry, vol. 378, No. 1, Jul. 1, 2008, pp. 93-95.
Zoppi et al. Radiocarbon, vol. 49, No. 1, Apr. 2007, pp. 173-182.
International Search Report for PCT/GB2008/002464, Oct. 24, 2008.
L.K. Fifield,Rep Prog Phys62, (1999), p. 1223-1274.
R.C. Garner et al.,Drug Metab Dispos, 30, (2002), p. 823-30.
R. C. Garner,Curr Drug Metab. 1, (2000), p. 205-213.
Lappin, G. & Garner, R.C., Chapter 11,Ultra-sensitive detection of radiolabelled drugs and their metabolites using accelerator mass spectromety, Handbook of Analytical Separations, Editor: I. Wilson,. 2003, Elsevier: Amsterdam. p. 331-349.
G. Lappin, et al.,Expert Opin. Drug Metab Toxicol, 2, (2006), p. 419-427.
G. Lappin et al.,Clin Pharmacol Ther, 80, (2006), p. 203-215.
G. Lappin, and S. Temple,Accelerator Mass Spectrometryin:Radiotracers in Drug Development, Taylor and Francis CRC Press, Florida, USA, (2006) p. 53-37.
G. Lappin et al.,Nat. Rev., 2, (2003), p. 233-240.
G. Laprin et al.,Expert Opin Drug Metab Toxicol, 4, (2008), p. 1021-1033.
N. Sarapa et al.,J Clin Pharmacol, 45 (2005), p. 1198-205.
J.S. Vogel,Biotechniques, 38, (2005), p. 25-9.
J.S. Vogel,Radiocarbon, 34, (1992), p. 344-350.
J.S. Vogel, and A.H. Love,Quantitating Isotopic Molecular Labels with Accelerator Mass Spectrometry: A.L. Burlingame, (Ed.), Methods in Enzymology, Academic Press, New York, (2005), p. 4020-422.
I.N. White, et al.,Trends in Pharmacol Sci., 25 (2004), p. 442-7.

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