Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1987-11-19
1991-10-08
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
530387, 530388, 435 7021, 4351722, C12N 520, C12N 1502, C07K 1528, C12P 2108
Patent
active
050554050
ABSTRACT:
Monoclonal antibody to Treponema denticola JD-1 and Treponema species 10A and a continuous cell line for its production is disclosed. These antibodies are particularly useful in immunoassays for detecting the presence of these microorganisms in the oral cavity.
REFERENCES:
patent: 4741999 (1988-05-01), Genco et al.
Tall et al.; "Characterization of Outer Membrane Proteins of Treponema denticola with Monoclonal and Polyclonal Antibodies", Abs. Ann. Mtg. Amer. Soc. Microbio. (1986).
Tall et al.; "Microscopic Agglutination and Polyacrylamide Gel Electrophoresis Analyses of Oral Anerobic Spirochetes", J. clin. Microbiol 24; 2; (1986) pp. 282-287.
Simonsen et al.; "Monoclonal Antibodies that Recognize a Specific Surface Antigen of Treponema denticola", Infect. Immun. 56, 1 (Jan. 1988) pp. 60-63.
Jacob et al.; "Detection of Elevated Serum Antibodies to Treponema denticola in Humans with Advanced Periodontitis by an Enzyme-Linked Immunosorbent Assay", Journal of Periodontal Research 17: 145-153, (1982) pp. 145-153.
Biemer Thomas A.
Mink Ronald
Sturdivant Linda D.
Wang Dou-Mei
Bell Craig M.
Hutzell Paula
Kepplinger Esther L.
Scola, Jr. Daniel A.
Warner-Lambert & Company
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