Process for the manufacture of 5-sulfamoyl-anthranilic acids

Details Process for the manufacture of 5-sulfamoyl-anthranilic acids Process for the manufacture of 5-sulfamoyl-anthranilic acids

1975-02-12

1977-01-04

Meyers, Albert T.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602396, C07C14378, C07C14380

Patent

active

040012840

ABSTRACT:
A process for the manufacture of sulfamoyl anthranilic acids of the general formula I ##STR1## in which Ph is phenyl substituted with 1 or 2 halogen atoms, alkyl groups or etherified hydroxy groups, and R is aralkyl, heteroaralkyl or cycloalkyl-alkyl, unsaturated in the aliphatic moiety, including oxygen or sulfur and/or substituted with halogen, alkyl or alkoxy in the aromatic moiety, by reacting carboxylic acids with at least one mol-equivalent of an amine

REFERENCES:
patent: 3658990 (1972-04-01), Werner
patent: 3793311 (1974-02-01), Feit et al.
J. of Chem. Soc., pp. 1168-1173 (1927), LeFevre et al., "The Scission of Diaryl Ethers and . . ., Piperdine."
"Mechanism and Structure in Org. Chemistry," Gould, Henry Holt & Co., New York, pp. 429 and 434 (1959).
J. Med. Chem. 15(1), 79-83 (1971), Feit et al., "Aminobenzoic Acid Diuretics . . . Derivatives.

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