Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure
Reexamination Certificate
1999-05-19
2001-08-21
Marx, Irene (Department: 1651)
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
C424S114000, C424S170100
Reexamination Certificate
active
06277374
ABSTRACT:
BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to yeast and mold (fungus) inhibiting products produced by Lactobacillus species, particularly a
Lactobacillus casei
having the essential identification characteristics of
Lactobacillus casei
var.
rhamnosus
NRRL-B-15972. In particular, the present invention relates to a process for producing the products and to their use in preventing yeast and mold growth in foods and other materials.
(2) Prior Art
Various substances are produced by microorganisms which are antimicrobial in character. Lactobacillus are known to produce metabolic products that are antibacterial and allow them to compete more effectively in certain environments. It is not believed to be known that lactobacilli produce any separately isolatable metabolic products which inhibit yeast and mold.
OBJECTS
It is therefore an object of the present invention to provide novel Lactobacillus metabolic products which inhibit yeast and mold and which are referred to herein as “FIC” or fungal inhibiting compounds. Further it is an object of the present invention to provide a process for producing the FIC products as well as a method for using these FIC products in foods and other materials. These and other objects will become increasingly apparent by reference to the following description.
REFERENCES:
patent: 3689640 (1972-09-01), Shahani et al.
patent: 4956177 (1990-09-01), King
patent: 8001045 (1980-08-01), None
patent: 1109436 (1984-08-01), None
Vincent et al., J. Bacteriol. vol. 78, pp 477-484 (1959).
ATCC Catalogue of Bact. pp. 115-118 (1989).
Rehm et al., “Biotechnology” vol. 5, p 73 (1983).
Condensed Chemical Dictionary p 502 (1974).
The Merck Index, p 768 (1983).
Dairy Microbiology, pp. 355-360 (Prentice Hall, Inc. 1957).
King Stephen W.
Vandenbergh Peter A.
Marx Irene
McLeod Ian C.
Microlife Technics, Inc.
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