Preparation of 3-formyltetrahydrothiopyrans

Details Preparation of 3-formyltetrahydrothiopyrans Preparation of 3-formyltetrahydrothiopyrans

1984-09-10

1986-12-16

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D33502

Patent

active

046297995

ABSTRACT:
3-Formyltetrahydrothiopyrans are prepared by hydrogenating a 3-formyl-5,6-dihydro-2H-thiopyran in the presence of a catalyst containing nickel, cobalt, platinum, copper and/or silver; if necessary, the 3-formyl-5,6-dihydro-2H-thiopyrans are prepared by converting bis-(.beta.-formylethyl) sulfides and/or 3-formyl-4-hydroxytetrahydrothiopyrans in the presence of an acidic catalyst, and, if required, these bis-(.beta.-formylethyl) sulfides and/or 3-formyl-4-hydroxytetrahydrothiopyrans are prepared by reacting an acrolein with hydrogen sulfide (a) in the presence of a basic catalyst and of methylene chloride, aromatic hydrocarbons and/or 1,1,2-trichloroethane as solvents, and/or (b) in the presence of a carboxamide.
The compounds obtainable by the process according to the invention are useful starting materials for the preparation of dyes, drugs and pesticides.

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