Chemistry: molecular biology and microbiology – Apparatus – Bioreactor
Patent
1997-05-21
1999-05-11
Beisner, William H.
Chemistry: molecular biology and microbiology
Apparatus
Bioreactor
4352971, 435182, 435382, 424424, 424 937, C12M3/06
Patent
active
059027452
ABSTRACT:
The present invention is directed to a cell encapsulation device that permits rapid and straightforward cell transfer into the device. The preferred device includes components that allow a user to quickly transfer cells into the device with minimal risk to the cells. Among the most important improvements of the present invention are: automatic filtration of excess solution during cell transfer; an instantly wettable cover, allowing ready view into the cell chamber; and a swellable core, allowing cells to be transferred with minimal shear force while assuring optimal cell placement in the device during use. The device of the present invention may be used either in vivo, such as to deliver therapeutic substances, or in vitro, such as to serve as a bioreactor.
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Butler Mark D.
Drumheller Paul D.
Mish Stanley L.
Beisner William H.
Gore Hybrid Technologies, Inc.
Sheets Eric J
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