Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1986-12-08
1989-09-05
Ford, John M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514274, 514349, 514351, 544239, 544241, 544316, 544317, 546297, 546300, A61K 31505, A61K 3150, C07D23714, C07D23934
Patent
active
048639249
ABSTRACT:
An N-benzoyl urea compound having the formula: ##STR1## wherein X is a hydrogen atom, a halogen atom or a nitro group, n is an integer of from 1 to 3, and Q is ##STR2## wherein Y.sub.1 is an unsubstituted or substituted alkyl group, or an alkoxy or alkoxycarbonyl group with its alkyl moiety unsubstituted or substituted, Y.sub.2 is a hydrogen atom, a halogen atom, a nitro group, an unsubstituted or substituted alkyl group, or an alkoxy or alkoxycarbonyl group with its alkyl moiety unsubstituted or substituted, Z is a hydrogen atom, a halogen atom, a trifluoromethyl group or a nitro group, and each of A and B is .dbd.CH-- or a nitrogen atom, provided that one of A and B is .dbd.CH-- and the other is a nitrogen atom, with the provisos (1) that when Q is ##STR3## where when X is a hydrogen atom and Y.sub.1 is an alkyl group, Z is not a hydrogen atom, a halogen atom nor a trifluoromethyl group, and (2) that when Q is ##STR4## wherein A is a nitrogen atom and Y.sub.1 is a trifluoromethyl group, Y.sub.2 is other than a hydrogen atom.
REFERENCES:
patent: 4677110 (1987-06-01), Haga et al.
Chemical Abstracts, vol. 98, 1983, p. 67, abstract No. 101183r Columbus, Ohio, U.S.; S. Garattini et al.: "Advance in Pharmacology and Chemotherapy" vol. 19, Academic Press, New York 1982, 294 pp.
Chemical Abstract, vol. 98 entry 101190r (1983) Ishihara.
Haga Takahiro
Koyanagi Toru
Okada Hiroshi
Sugi Hideo
Yamada Nobutoshi
Ford John M.
Ishihara Sangyo Kaisha Ltd.
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