Prolinal derivatives having inhibitory activity on prolyl endope

Details Prolinal derivatives having inhibitory activity on prolyl endope Prolinal derivatives having inhibitory activity on prolyl endope

1990-06-12

1992-05-12

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548517, 548525, 548527, C07D40506, C07D40508, A61K 3134, A61K 3135

Patent

active

051128470

ABSTRACT:
Prolinal derivatives of the formula ##STR1## wherein A is a group of the general formula ##STR2## wherein one of R.sup.1 and R.sup.2 is a hydrogen atom and the other is an alkyl group of from 2 to 5 carbon atoms, alkoxy group of from 1 to 5 carbon atom(s), phenyl group, benzyl group, cycloalkyl group of from 4 to 6 carbon atoms or (cycloalkyl group of from 4 to 6 carbon atoms)--methyl group or R.sup.1 and R.sup.2 each represent the same or different alkyl group of from 1 to 4 carbon atom(s) or a group of the formula ##STR3## wherein m represents an integer of from 3 to 6, n represents an integer of from 3 to 10, D represents a specified heterocyclic ring which is unsubstituted or substituted. These derivatives possess inhibitory activity on prolyl endopeptidase and therefor are useful as treating and/or preventing agents for amnesia.

REFERENCES:
patent: 4956380 (1990-09-01), Toda et al.

Affiliated with

Also associated with

Rating

Prolinal derivatives having inhibitory activity on prolyl endope does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Prolinal derivatives having inhibitory activity on prolyl endope, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prolinal derivatives having inhibitory activity on prolyl endope will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2426217