6-(imidazolyphenyl)-4-iminopyrimidinones useful as hypotensive a

Details 6-(imidazolyphenyl)-4-iminopyrimidinones useful as hypotensive a 6-(imidazolyphenyl)-4-iminopyrimidinones useful as hypotensive a

1986-09-24

1987-11-24

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544317, A61K 31415, C07D23910

Patent

active

047089580

ABSTRACT:
This invention relates to novel 6-(imidazolylphenyl)-4-iminopyrimidinone compounds having antihypertensive and platelet aggregation inhibition activity.
More particularly, the present invention relates to a novel class of pyrimidinone derivatives represented by the formula ##STR1## and the pharmaceutically acceptable salts thereof wherein X may be one to three substituents selected from the group consisting of R,--OR,--SR,--NHR,--NR.sub.2, Cl, Br, F, NO.sub.2,--COCH.sub.3, --COOH,--COOR,--CONHR,--CONR.sub.2, and --OH; and where R represents lower alkyl having 1-6 carbon atoms.

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