Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1996-11-06
1998-10-20
Azpuru, Carlos A.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424 7837, 525408, 525413, 525415, 525450, 528352, 528361, 604 93, 623 13, 623 14, A61F 202, A61F 208, A61K 31765, C08G 6391
Patent
active
058243330
ABSTRACT:
The present invention provides injectable, bioabsorbable liquid copolymers suitable for use as a soft tissue repair or augmentation material in animals comprising a liquid polymer selected from the group consisting of liquid polymers of a plurality of at least two different first lactone repeating units and liquid polymers of a plurality of first lactone and second lactone repeating units; wherein the first lactone repeating units are selected from the group consisting of .epsilon.-caprolactone repeating units, trimethylene carbonate repeating units, ether lactone repeating units (which for the purpose of this invention shall mean 1,4-dioxepan-2-one and 1,5-dioxepan-2-one) and combinations thereof and the second lactone repeating units are selected from the group consisting of glycolide repeating units, lactide repeating units (which for the purpose of this invention are defined to be L-lactide, D-lactide, or D,L-lactide repeating units), p-dioxanone repeating units and combinations thereof. Additionally, the present invention also discloses methods of using these liquid copolymers for tissue augmentation and repair as well as kits which include prefilled containers to facilitate the use of these materials.
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Arnold Steven C.
Bezwada Rao S.
Scopelianos Angelo G.
Azpuru Carlos A.
Ethicon Inc.
Woodrow Hal Brent
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