Injectable therapeutic compositions containing stable S-adenosyl

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 45, 536 26, 536 24, C07H 19167

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active

051149311

ABSTRACT:
The invention discloses injectable therapeutic compositions containing stable S-adenosyl-L-methionine (SAMe) salts as an active ingredient. Injectable therapeutic compositions which permit large doses of SAMe to be administered by injection, at physiological pH having excellent tolerability has been achieved by administering SAMe salts in an aqueous solution which is adjusted to a pH of between 5 and 8.5 containing an amino acid and an alkaline base in critical proportions.

REFERENCES:
patent: 3893999 (1975-07-01), Fiecchi
Ikezuki et al., Chem. Abstr., 71:94778a, 1969 (Ger. Patent #1,808,948).
Okazaki et al., Chem. Abstr., 83:152337s, 1975.
Good et al., Chem. Abstr., 64:10068b, 1966.

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