Fluorescent conjugates for analysis of molecules and cells

Details Fluorescent conjugates for analysis of molecules and cells Fluorescent conjugates for analysis of molecules and cells

1985-02-13

1989-08-22

Brown, Johnnie R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 6, 436519, 436501, 436547, 436800, 436805, 530807, 536 27, C12Q 170, G01N 33566, G01N 33554, G01N 3353

Patent

active

048595829

ABSTRACT:
Sensitive detection techniques and compositions for such techniques are provided by employing fluorescent proteins having bilin prosthetic groups as labels. The bilin containing proteins can be conjugated to ligands or receptors for use in systems involving ligand-receptor binding for the analysis, detection or separation of ligands and receptors. Particularly, one or more of the bilin containing proteins may be used as labels in conjunction with each other or other fluorescers for defining subsets of naturally occurring aggregations e.g. cells.

REFERENCES:
patent: 4520110 (1985-05-01), Stryer et al.
patent: 4542104 (1985-09-01), Stryer et al.
Eder, J. et al., Biochemistry, vol. 15, 1978, pp. 315-321.
Chemical Abstracts, vol. 57, Sept., 1962, Abstract No. 6493e, Saha, S.
Chemical Abstracts, vol. 76, No. 11, 1972, p. 138, Abstract No. 55529d, Glazer, A. N., et al.
Chemical Abstracts, vol. 87, No. 23, 1977, p. 321, Abstract No. 180,925h, Gantt, E., et al.

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