Rhenium generator system and its preparation and use

Details Rhenium generator system and its preparation and use Rhenium generator system and its preparation and use

1988-01-25

1989-08-22

Hunt, Brooks H.

Chemistry of inorganic compounds

Treating mixture to obtain metal containing compound

Radioactive metal

423 49, 423 55, 423 58, 252645, 376158, 376189, 250432PD, 424 11, C01G 4700, C01G 4100, G21G 100, A61K 4300

Patent

active

048594318

ABSTRACT:
A process for preparing a tungsten-188/rhenium-188 generator having a tungstate matrix containing W-188 produced by irradiating tungsten-186 in the tungstate compound. High activity, carrier-free rhenium-188 may be obtained by elution. Substrates for further purifying the rhenium-188 eluate are also described.

REFERENCES:
patent: 3332737 (1967-07-01), Kraus
patent: 4280053 (1981-07-01), Evans
patent: 4738834 (1988-04-01), Moore et al.
J. Evans et al., Appl. Radiat. Isot., vol. 38, No. 1, pp. 19-29, 1987, Int. J. Radiat. Appl. Instrum., Part A.
W. Rieman and H. Walton, Ion Exchange in Analytical Chemistry, Chapter 8, pp. 140-142 and 144-145, Pergammon Press, Oxford, New York, 1970.
Blachot, J. et al., "Un Generateur de.sup.188 Re a Partir de.sup.188 W", International Journal of Applied Radiation and Isotopes, vol. 20, pp. 467-470, 1969.
Kordyukevich, V. O. et al., "Extractive Separation of Rhenium Isotopes Without Carriers from a Tungsten Target", Radiokhimya, vol. 26, No. 5, pp. 625-629, 1984.
Evans, J. V. et al., "A New Generator for Technetium-99m", purportedly presented at 3rd World Congress Nuclear Medicine & Biology, Paris, Aug. 1982.
Narasimhan, D. V. S. et al., "A New Method for .sup.99m Tc Generator Preparation", J. Radioanal. Nucl. Chem., Letters 85, 6, pp. 345-355, 1984.
Narasimhan, D. V. S. et al., "Preparation of a Sterile Closed System .sup.99m Tc Generator Based on Zirconium Molybdate", J. Radioanal. Nucl. Chem., Letters 85, 3, pp. 163-172, 1984.
Boyd, R. E., "Technetium-99m Generators-The Available Options", Int. J. Appl. Radiat. Isot., vol. 33, pp. 801-809, 1982.

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