Process for preparing quinazolinone oxides

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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260239BD, 2602455, 544285, 564 50, 564 52, C07D23982, A61K 31505

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active

042581877

ABSTRACT:
Improved process for the preparation of 6-substituted-4-phenylquinazolinone 3-oxides. Such compounds are useful as intermediates in the preparation of 3-fluorobenzodiazepines, which are useful as tranquilizers, muscle relaxants and sedatives.

REFERENCES:
patent: 3923803 (1975-12-01), Inaba et al.
patent: 3926993 (1975-12-01), Ishizumi et al.
Brown, Fused Pyrimidines; Quinazalines; Part I, pp. 78-80, 1967, Interscience.
Black, et al., "Synthesis", vol. 4, 1975, pp. 205-221.
Stamm, "Methodicum Chimicum", vol. 6, 1975, 329-401.

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