Phenoxy-amino-propanols

Details Phenoxy-amino-propanols Phenoxy-amino-propanols

1979-05-30

1981-03-24

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

564349, A61K 31135, C07C 9306

Patent

active

042580625

ABSTRACT:
New phenoxy-amino-propanols of formula ##STR1## wherein R.sup.1 is alkenyl, alkynyl, alkoxyalkyl or alkenyloxyalkyl with 2-6 C atoms in each case or cycloalkyl with 3-8 C atoms; and R.sup.2 is alkyl or hydroxyalkyl with 1-6 C atoms in each case, cycloalkyl with 3-8 C atoms, aralkyl or aralkyl wherein the aryl radical is mono- to tri-substituted by alkyl, alkoxy, OH, F and/or Cl or mono-substituted by methylenedioxy, with a total of 7-15 C atoms in each case, and the physiologically acceptable acid addition salts thereof, exhibit various pharmacological properties including isoprenaline-antagonism on the heart rate and blood pressure.

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patent: 3928601 (1975-12-01), Brandstrom et al.
patent: 3929856 (1975-12-01), Holmes et al.
patent: 3930016 (1975-12-01), Berntsson et al.
patent: 4084002 (1978-04-01), Koppe et al.
patent: 4145442 (1979-03-01), Berntsson et al.

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