Naphthalenyloxy substituted carboxylic acids

Details Naphthalenyloxy substituted carboxylic acids Naphthalenyloxy substituted carboxylic acids

1985-04-01

1986-06-10

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 56, 562462, 562466, C07C 6994

Patent

active

045944423

ABSTRACT:
Compounds of the formula ##STR1## wherein R is hydrogen or lower alkyl, X is hydrogen or halogen, and A is the group ##STR2## wherein R.sub.1 is hydrogen, acyl or lower alkyl, R.sub.2 is hydrogen or lower alkyl, m is an integer from 2 to 4, n is an integer from 1 to 3, and t is an integer from 1 to 5, provided that R.sub.1 is adjacent to --(CH.sub.2).sub.m --O(CH.sub.2).sub.m ].sub.n O--, and, when R.sub.2 is hydrogen, salts thereof with pharmaceutically acceptable bases, are described. The compounds of formula I are useful as agents for the treatment of allergic conditions.

REFERENCES:
patent: 3642869 (1972-02-01), Narayanan et al.
patent: 3740437 (1973-06-01), Harrison et al.
patent: 4207241 (1980-06-01), Fried et al.
patent: 4414405 (1983-11-01), Giordano et al.
patent: 4417070 (1983-11-01), Arai et al.

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