3-Piperidino or apiperazino-1-phenyl or 1-substituted phenyl iso

Details 3-Piperidino or apiperazino-1-phenyl or 1-substituted phenyl iso 3-Piperidino or apiperazino-1-phenyl or 1-substituted phenyl iso

1979-09-12

1981-08-04

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602444, 4242484, 424258, 544128, 544363, 546 90, 546143, A61K 3147, A61K 31495, C07D40104

Patent

active

042822220

ABSTRACT:
Isoquinolines of the formula ##STR1## in which R.sub.1 is piperidino, piperazino or piperazino N-substituted thereof by alkyl of 1 to 4 carbon atoms, alkylene of 1 to 4 carbon atoms wherein said alkylene is substituted in turn by fluorobenzoyl, or CHO; R.sub.2 is phenyl or phenyl substituted by alkyl of 1 to 4 carbon atoms, halogen, amino or nitro; and R.sub.3 is hydrogen or halogen, a process for their preparation and medicaments containing the isoquinolines, especially the use of said medicaments as antidepressants.

REFERENCES:
patent: 3517005 (1970-06-01), Cronin et al.
patent: 3975524 (1976-08-01), Nickl et al.

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