Preservation of column materials in aqueous solutions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514452, A01N 4332, A01N 4380

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active

056188323

ABSTRACT:
Combination composed of 2-methyl-4-isothiazolin-3-one hydrochloride and 5-bromo-5-nitro-1,3-dioxane for the elimination of microbes as well as for the preservation of column materials in aqueous solutions. The biocidal mixture is preferably added at concentrations of 0.001 to 0.3% (w/v).

REFERENCES:
patent: 4906651 (1990-03-01), Hsu
patent: 5300424 (1994-04-01), Hoss et al.
Derwent Publications Ltd., AN 90-345639/46 & JP a-2- 250 805 Oct. 8, 1990.
Journal of Chromatography, BD 469, 1989, "Determination of Preservatives in Cosmetic Products" De Kruijf et al.
Varian Instrument Application, BD 11, NR. 3, 1977 "Preserving Liquid Chromatographic Column Life", B. Wadsworth.

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