Antimigraine 1,2,5-thiadiazole derivatives of indolylalkyl-pyrid

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514254, 544295, 544364, 544367, C07D41714, C07D40314, A61K 31495, A61K 31505

Patent

active

056188161

ABSTRACT:
A series of novel 5-(3,4-diamino-1,2,5-thiadiazole and S-oxide) derivatives of indolylalkylpiperazinyl pyridines and pyrimidines of Formula I are intended for use in the alleviation of vascular headaches. ##STR1## In Formula I, X is selected from S, SO and SO.sub.2.

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"Drugs Used to Treat Migraine and Other Headaches," Drug Evaluations, 6th edition, 1986, pp. 239-253.

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