DNA encoding human AlkB

Details DNA encoding human AlkB DNA encoding human AlkB

1995-06-05

1997-04-08

Wax, Robert A.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

4353201, 435 691, 435183, 435348, 435358, 435365, 435419, 536 232, C12N 500, C12N 1500, C12P 2106, C07H 1700

Patent

active

056187173

ABSTRACT:
A human hABH polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of mutations and the treatment of diseases which result from damaged DNA, for example, cancer. Antagonists against such polypeptides and their use as a therapeutic to augment chemotherapy of cancer cells are also disclosed.

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