Process for simultaneously disinfecting and fixing biological fl

Chemistry: molecular biology and microbiology – Maintaining blood or sperm in a physiologically active state...

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435 6, 435 31, 435 32, 435 91, 435810, 422 28, 422 29, 422 36, 514693, 514694, A01N 102, A01N 3500, A61L 200, C12Q 122

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056186649

ABSTRACT:
Methods and kits for reducing the transmission of infectious agents contained in biological fluid samples are provided. The methods include contacting the biological sample with a fixative solution containing a fixative present at a concentration sufficient to simultaneously disinfect the sample and fix analytes contained therein.

REFERENCES:
patent: 4675159 (1987-06-01), Al-Sioufi
patent: 4683202 (1987-07-01), Mullis
patent: 4880602 (1989-11-01), Al-Sioufi
patent: 5422277 (1995-06-01), Connelly et al.
Aloisio et al, J. Immunol. Methods, vol. 128, pp. 281-285, 1990.
Lifson et al, J. Immunol. Methods, vol. 86, pp. 143-149, 1986.
Li et al, Proc. Natl. Acad. Sci. USA, vol. 87, pp. 4580-4584, Jun. 1990.
Nicholson et al, J. Immunol. Methods, vol. 160, pp. 215-218, 1993.
M. Borzy et al., Detection of Human Immunodeficiency Virus in Cell-Free Seminal Fluid, J. of Acquired Immune Deficiency Syndromes, vol. 1, 1988, 419-424.
A. Kiessling et al., Human Immunodeficiency Virus Detection and Differential Leukocyte Counts are Accurate and Safer with Formaldehyde-Fixed Blood, Blood, vol. 81, 1993, 864-865.
L. Fitzgerald et al., PCR Amplification of HIV and Cellular DNA Sequences in Formaldehyde-Fixed, Immunoreactive White Blood Cells, BioTechniques, vol. 15, No. 1, 1993, 128-133.
A. Kiessling et al., Formaldehyde-fixed semen is suitable and safer for leukocyte detection and DNA amplification, Fertility and Serility, vol. 60, No. 3, Sep. 1993, 576-581.
J. Lifson et al., Utility of formaldehyde fixation for flow cytometry and inactivation of the AIDS associated retrovirus, J. of Immunological Methods, vol. 86, 1986, 143-149.
L. Martin et al., Disinfection and Inactivation of the Human T Lymphotropic Virus Type III/Lymphadenopathy-Associated Virus, J. of Infectious Diseases, vol. 152, No. 2, 1985, 400-403.
B. Spire et al., Inactivation of Lymphadenopathy Associated Virus by Chemical Disinfectants, The Lancet, Oct. 20, 1984, 899-901.
C. Aloisio et al., Recovery of infectious human immunodeficiency virus from cells treated with 1% paraformaldehyde, J. of Immunological Methods, vol. 128, 1990, 281-285.
J. Cory et al., Detection of human immunodeficiency virus-infected lymphoid cells at low frequency by flow cytometry, J. of Immunological Methods, vol. 105, 1987, 71-78.
L. Lanier et al., Paraformaldehyde Fixation of Hematopoietic Cells for Quantitative Flow Cytometry (FACS) Analysis, J. of Immunological Methods, vol. 47, 1981, 25-30.
M. Lai-Goldman et al., Detection of human immunodeficiency virus (HIV) infection in formalin-fixed, paraffin-embedded tissues by DNA amplification, Nucleic Acids Research, vol. 16, No. 16, 1988, 8191.
D. Shibata et al., Analysis of Human Immunodeficiency Virus and Cytomegalovirus Infection by Polymerase Chain Reaction in the Acquired Immunodeficiency Syndrome, Arch Pathol Lab Med, vol. 113, Nov. 1989, 1239-1244.
M. Holodniy et al., Detection and Quantification of Human Immunodeficiency Virus RNA in Patient Serum by Use of the Polymerase Chain Reaction , J. of Infectious Diseases, vol. 163, 1991, 862-865.
C. Lynch et al., Detection of HIV-1 DNA by PCR: Evaluation of Primer Pair Concordance and Sensitivity of a Single Primer Pair, J. of Acquired Immune Deficiency Syndromes, vol. 5, 1992, 433-440.
M. Poznansky et al., A Rapid Method for Quantitating the Frequency of Peripheral Blood Cells Containing HIV-1 DNA, J. of Acquired Immune Deficiency Syndromes, vol. 4, 1991, 368-373.
K. Young et al., Detection of HIV DNA in peripheral blood by the polymerase chain reaction: a study of clinical applicability and performance, AIDS, vol. 4, No. 5, 1990, 389-391.
B. Conway et al., Detection of HIV-1 DNA in Crude Cell Lysates of Peripheral Blood Mononuclear Cells by the Polymerase Chain Reaction and Nonradioactive Oligonucleotide Probes, J. of Acquired Immune Deficiency Syndromes, vol. 3, 1990, 1059-1064.
J.P. Clewley, The polymerase chain reaction, a review of the practical limitations for human immunodeficiency virus diagnosis J. of Virological Methods, vol. 25, 1989, 179-186.
C. Ou et al., DNA Amplification of Direct Detection of HIV-1 in DNA of Peripheral Blood Mononuclear Cells, Science, vol. 239, Jan. 15, 1988, 295-297.
S. Kwok et al., Identification of Human Immunodeficiency Virus Sequences by Using In Vitro Enzymatic Amplification and Oligomer Cleavage Detection, J. of Virology, May 1987, 1690-1694.
M. DaSilva et al., Detection of HIV-Related Protein in Testes and Prostates of Patients with AIDS, A.J.C.P., vol. 93, No. 2, Feb. 1989, 196-201.
M. El-Demiry et al., Identifying Leucocytes and Leucocyte Subpopulations in Semen Using Monoclonal Antibody Probes, Urology, vol. 28, No. 6, Dec. 1986, 492-496.
R. Warnke et al., Diagnosis of Human Lymphoma with Monoclonal Antileukocyte Antibodies, New England J. of Medicine, vol. 309, No. 21, Nov. 24, 1983, 1275-1281.
Lifson, J.D. et al., Variables Affecting T-Lymphocyte Subsets in a Volunteer Blood Donor Population, Clin. Clin. Immunol and Immunopathol. 36:151-156 (1985).

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