Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1994-07-06
1997-04-08
Cunningham, Thomas M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
4241851, 4241921, 4242651, 435 693, 530350, 530395, 530403, A61K 3900
Patent
active
056185421
ABSTRACT:
This invention relates to polypeptide antigens of T.ovis suitable for use in vaccines to protect ruminants against infection by cestode parasites, The antigens are preferably obtained by expression of DNA coding therefor in a recombinant host cell. Aspects of the invention include DNA encoding the antigens, vectors containing the DNA and hosts which express the antigens.
The invention also provides antibody and DNA probes for use in identifying protective antigens of cestode parasites other than T.ovis.
REFERENCES:
patent: 5348740 (1994-09-01), Harrison et al.
patent: 5366728 (1994-11-01), Harrison et al.
J. Mol. Biochem Parasitol, 1988, 28 (1988), pp. 21-30.
Nature, 1989, 338 (621), pp. 585-587.
Adv. Parasitology, 21, (1982), pp. 230-296.
Howell, M. J. et al "Cloning and expression of T . . . ", Mol. Biochem. Parasitol, 28, pp. 21-30.
Craig, P.S. et al "Antibody responses . . . " Z. Parasitol, 67 (2), pp. 197-209.
Osborn, P.J. et al. "Vaccination of . . . " Res. Vet. Sci., 32 (3) 1982 (abstract only), pp. 350-353.
Dempster Robert P.
Harrison Gavin B. L.
Heath David D.
Johnson Kevin S.
Lawrence Stephen B.
Coopers Animal Health NZ Limited
Cunningham Thomas M.
Ministry of Agriculture & Fisheries
University Of Melbourne
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