Vaginal ring

Details Vaginal ring Vaginal ring

1987-02-13

1989-04-18

Swisher, Nancy A. B.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

6048911, 424430, A61M 700

Patent

active

048226165

ABSTRACT:
A vaginal ring comprises a supporting ring 1 free of active agent. A layer 2, which contains an active agent such as a steroid, is applied on its outer rim, optionally in a continuous groove provided in the supporting ring. This layer, in turn, is coated with a layer 3 devoid of active ingredient. All components preferably comprise an LTV silicone elastomer. The ratio of the thickness of the layer 2, containing an active agent, to the layer 3, free of active agent, is about 5-50:1. As a result, a long-term and uniform release rate is achieved for the active agent.

REFERENCES:
patent: 4012496 (1977-03-01), Schopflin et al.
patent: 4012497 (1977-03-01), Schopflin
patent: 4155991 (1979-05-01), Schopflin et al.
patent: 4292965 (1981-10-01), Nash et al.

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