Human cytokine polypeptide

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 691, 435 6, 435455, 435471, 4352523, 43525411, 435325, 4353201, 536 231, 536 235, 536 2351, C07H 2100, C12N 1516, C12N 1563, C12N 510, C12N 115, C12N 121

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060080221

ABSTRACT:
The invention relates to human cytokine polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.

REFERENCES:
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Orkin et al. "Report and recommendations of the panel to assess the NIH investment in research on gene therapy", issued by the U.S. National Institutes of Health, Dec. 1995.
Jahn et al., Gene 133(1):71-78 (1993).
Genbank Accession No. AA304448 (Apr. 18, 1997), Adams et al.
Mason et al., Genes and Development 8:1489-1501 (1994).
Glucksmann-Kuis et al., Cell,81(2):289-298 (1995).
Genbank Accession No. T52467 (Feb. 06, 1995).
Hillier et al., Wash U-Merck EST Project,(1995).
Kireeva et al., Molecular and Cellular Biology, 16(4):1326-1334 (1996).
B. Cullen, Methods in Enzymology, 152:684-704 (1987).
George et al., Macromolecular Sequencing and Synthesis Selected Methods and Applications, 127-149 (1988).

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