Process for preparing epoxy-heparides, the products obtained and

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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536 21, 536 54, 536 55, 536 551, 536 56, A61K 31725, C07H 310, C07H 506

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054038278

ABSTRACT:
There is provided a process for preparing epoxy-heparide polysaccharides of formula (I): ##STR1## wherein A is a pyran ring with substituents 1 and 4 in the axial position and 5 in the equatorial position, and R and R' are hexosamines which constitute a polysaccharide chain bonded to said ring A by a glucoside, and one of R and R' is H when the ring A is in the terminal position of said polysaccharide chains, and said heparide has a COCH.sub.3 to COOH ratio of 0.5, said process comprising

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Jaseja et al. Can. J. Chem. 1989, 67(9), 1449-1456.

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