Antimicrobial medical devices

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

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604 20, 604 21, A61M 532

Patent

active

053242750

ABSTRACT:
A catheter assembly is described which comprises a catheter tube, an exterior portion of which is circumferentially surrounded by at least two parallel elongated helical conductive elements which may be operably connected to a first power source to create a first open circuit to induce an antimicrobial effect in the area proximate the exterior conductive elements through oligodynamic activity. The catheter assembly further comprises a hub at its proximal end having a cap containing a second power source. At least two internal conductive elements are disposed along the internal length of the hub and are operably connected to the second power source upon closure of the hub with the cap to create a second open circuit which creates an antimicrobial effect proximate the hub through oligodynamic activity.

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Spadaro et al., "Anitbacterial Effects of Silver Electrodes with Weak Direct Current," 6 Antimicrobial Agents and Chemotherapy 637-642, Nov. 1974.
Berger et al., "Electrically Generated Silver Ions: Quantitative Effects on Bacterial and Mammalian Cells," 9 Antimicrobial Agents and Chemotherapy 357-358, Feb. 1976.
Maki et al., "An Attachable Silver-Impregnated Cuff for Prevention of Infection with Central Venous Catheter: A Prospective Randomized Multicenter Trail," 85 The American Journal of Medicine 307-314, Sep. 1988.
Flowers et al., "Efficacy of an Attachable Subcutaneous Cuff for the Prevention of Intravascular Catheter-Related Infection," 261 Journal of the American Medical Association 878-883, Feb. 10, 1988 Commerical VitaCuff.RTM., in publication since approx. 1988.

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