Novel type of oxa- and thia-steroids

Details Novel type of oxa- and thia-steroids Novel type of oxa- and thia-steroids

1978-01-16

1978-12-19

Randolph, John D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603459S, C07D30910, C07D33502

Patent

active

041305655

ABSTRACT:
16-Oxa- and 16-thia-D-homo-estrogen derivatives useful as postcoital oral contraceptives which are produced by total synthesis from 1-vinyltetralin-1-ols or their thiuronium derivatives on reactions with 4-substituted tetrahydropyran- or tetrahydrothiopyran-3,5-diones, and subsequent appropriate modifications.

REFERENCES:
patent: 4083852 (1978-04-01), Terasawa et al.
Sih et al., J. Am. Chem. Soc., vol. 87, pp. 1386-1387, (1965).
Grens et al., Chem. Abstracts, abst. No. 58968w, vol. 67, 1967.
Degani et al., Chem. Abstracts, abst. No. 29543u, vol. 68, 1968.

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