Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-10-14
1981-12-22
Ford, John M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424270, 546280, 548197, A61K 3144, C07D41712
Patent
active
043071040
ABSTRACT:
The compounds of this invention are 2,3-unsaturated nitrogen containing heterocyclic compounds with a 3-nitro group and a 2-(2-guanidino-4-thiazolyl alkylamino) group. These compounds have histamine H.sub.2 -antagonist activity. A particular compound of this invention is 2-[2-(2-guanidino-4-thiazolylmethylthio)ethylamino]-3-nitro-1,4,-5,6-tetra hydropyridine.
REFERENCES:
patent: 4165377 (1979-08-01), Jones et al.
patent: 4165378 (1979-08-01), Gilman et al.
patent: 4238493 (1980-12-01), Roantree et al.
Derwent Abstract 36952C (European Patent 10,894) May 14, 1980.
Roantree Michael L.
Young Rodney C.
Dentz Bernard
Foggio Richard D.
Ford John M.
Keps Joan S.
Lourie Alan D.
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